Desonide

Product Name: Desonide
CAS No.: 638-94-8
Chemical Name: Desonide
Synonyms: Tridesilon;PREDNACINOLONE;d-2083;Topifug;The Ned;DESONIDE;Locapred;Desonade;steroderm;Be Consolide
CBNumber: CB2783466
Molecular Formula: C24H32O6
Formula Weight: 416.51
MOL File: 638-94-8.mol

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Desonide Property

Melting point:: 272-274?C
Boiling point:: 580.1±50.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated)
form: Solid
pka: 12.87±0.10(Predicted)
color: White to Off-White
CAS DataBase Reference: 638-94-8(CAS DataBase Reference)

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Safety

HS Code: 2937290000
Toxicity: LD50 in rats (mg/kg): 93 s.c. (Phillips)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS021596
Product name: Desonide
Packaging: 50MG
Price: $37.8
Updated: 2022/05/15

TCI Chemical

Product number: D5578
Product name: Desonide
Packaging: 250MG
Price: $27
Updated: 2024/03/01

TCI Chemical

Product number: D5578
Product name: Desonide
Packaging: 1G
Price: $75
Updated: 2024/03/01

Cayman Chemical

Product number: 21368
Product name: Desonide
Purity: ≥98%
Packaging: 50mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 21368
Product name: Desonide
Purity: ≥98%
Packaging: 100mg
Price: $176
Updated: 2024/03/01

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Desonide Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Originator

Tridesilon,Dome,US,1972

Uses

Desonide(Budesonide EP Impurity F) is an impurity of Budesonide (B689490), an anti-inflammatory.

Uses

antifungal

Uses

Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).

Definition

ChEBI: Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.

Indications

Desonide (DesOwen, Tridesilon) is a synthetic corticosteroid.

Manufacturing Process

Preparation of 11β,21-Dihydroxy-16α,17α-Isopropylidenedioxy-1,4- Pregnadiene-3,20-Dione: A solution of 11β,16α,17α,21-tetrahydroxy-1,4- pregnadiene-3,20-dione (40 mg) in acetone (10 ml) containing hydrochloric acid (three drops; d 1.19) is boiled 3n the steam bath for two minutes and then allowed to stand for eighteen hours at room temperature. The reaction mixture is diluted with water (50 ml) and extracted with chloroform (3x25 ml), the combined extracts then being washed with water (30 ml) and dried over anhydrous sodium sulfate. The residue obtained by removal of solvent crystallized from ethyl acetate-petroleum ether as small plates (25 mg), melting point 257°-260°C.

brand name

Desowen (Galderma); Tridesilon (Perrigo).

Therapeutic Function

Antiinflammatory

Desonide Preparation Products And Raw materials

Raw materials

Preparation Products

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Desonide Suppliers

Americas 1 Belgium 2 Brazil 1 Canada 3 China 347 Europe 3 France 1 Germany 3 India 41 Israel 2 Italy 2 Japan 1 Malaysia 1 Nepal 1 Philippines 1 South Korea 1 United Kingdom 8 United States 40 Venezuela 1 Global 460

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10658
Advantage: 60

Alfa Chemistry

Tel: +1-5166625404
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 21317
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Accela ChemBio Inc.

Tel: (+1)-858-699-3322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 19965
Advantage: 58

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10413
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

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View Lastest Price from Desonide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Desonide 638-94-8
Price: US $70.00-700.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-06

Wuhan Boyuan Import & Export Co., LTD

Product: Desonide 638-94-8
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000tons
Release date: 2023-07-11

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Desonide 638-94-8
Price: US $380.00/gram
Min. Order: 100gram
Purity: 99% HPLC
Supply Ability: 20 tons
Release date: 2022-10-21

638-94-8, DesonideRelated Search:

(r)-budesonide Ciclesonide 11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 14,15-Dehydro Budesonide 9α-BroMobudesonide 16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers) LY2228820 Meprednisone Dienogestrel Clopidogrel Bisulfate LY 2157299 Budesonide Di-Norbudesonide (Mixture of DiastereoMers) 9,11-Anhydrobudesonide 21-Acetoxy-11β-hydroxy-16α,17α-propylmethylenedioxpregna-1,4-diene-3,20-dione (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione 1,2-Dehydrobudesonide Budesonide Sulfate SodiuM (Mixture of DiastereoMers)

PREDNACINOLONE

DESONIDE

1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE

(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione

16-alpha-hydroxyprednisole-16,17-acetonide

17-acetonide,16-alpha-hydroxy-prednisolone-1

d-2083

steroderm

Desonidemicro

(11β,16α)-11,21-Dihydroxy-16,17-[(1-Methylethylidene)bis(oxy)]pregna -1,4-diene-3,20-dione

16α-Hydroxyprednisolone Acetonide

(11,16a)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

16a-Hydroxyprednisolone Acetonide

Locapred

Topifug

Tridesilon

Be Consolide

16a-Hydroxyprednisole-16,17-acetonide

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-

Desonide (250 mg)

Desonide, >=99%

Budesonide EP Impurity F(Desonide)

16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione

Budesonide impurity F

Budesonide Impurity F (Desonide)

DesonideBiocar

Budesonide Impurity 6(Budesonide EP Impurity F)

Budesonide iMpurit F

Budesonide EP Impurity F

11beta,21-Dihydroxy-16alpha,17alpha-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-

Desonide Solution in Acetonitrile, 100μg/mL

(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

(11beta,16alpha)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

Budesonide Acetonide

Desonide USP/EP/BP

DesonideQ: What is Desonide Q: What is the CAS Number of Desonide Q: What is the storage condition of Desonide

16a,17-[1-Methylethylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Desonide (1173304)

The Ned

-Amino-2-methyl-283H-tetrazole

Desonide (Budesonide acetonide)

API Steriods Desonide Powder Dosage Usage Effect and Benefit

16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-

Desonide (Budesonide EP Impurity F)

Desonide EP Impurity-E

1, 4-PREGNADIEN-11β, 16α, 17, 21-TETROL-3, 20-DIONE 16, 17-ACETONIDE

Desonide/(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

Desonade

(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

638-94-8

C24H32O6

SPORANOX

Hormone Drugs

Chiral Reagents

Intermediates & Fine Chemicals

Pharmaceuticals